> THERAPEUTIC INDICATION

LOPINE contains the active substance amlodipine which belongs to a group of medicines called calcium channel blockers.
LOPINE is used to treat increased blood pressure (hypertension), or a certain type of chest pain called angina, a rare form of which is Prinzmetal's angina.
In patients with high blood pressure, your medicine works by relaxing the blood vessels so that blood flows through them more easily.
In patients with angina, LOPINE works by improving the blood supply to the heart muscle so that it receives more oxygen, thus preventing chest pain. Your medicine does not provide immediate relief for angina-related chest pain.

> DOSAGE AND ADMINISTRATION

Always take this medicine exactly as directed by your doctor or pharmacist. Check with your doctor or pharmacist if you are not sure.
The usual starting dose of LOPINE is 5 mg once a day. This dose may be increased to 10 mg once daily.
Your medicine can be used before or after food and drink. It is best to take your medicine at the same time every day with a glass of water. Do not take LOPINE with grapefruit juice.
It is important to keep taking the tablets. Do not wait until you have taken all your tablets before consulting your doctor.
Use in children and adolescents: For children and adolescents (6 to 17 years of age), the usual recommended starting dose is 2.5 mg per day. The maximum recommended dose is 5 mg per day. LOPINE 2.5 mg tablets are not currently available.

Prescription medicine. Ask your doctor for advice.