> THERAPEUTIC INDICATION
UPRAJECT is a “selective proton pump inhibitor”, a medicine that reduces the amount of acid your stomach produces. It is a preparation intended to treat gastric and intestinal pathologies linked to acidity.
This preparation is injected into the vein and will only be prescribed if your doctor feels that pantoprazole injections are more appropriate for you at that time than pantoprazole tablets. The tablets will replace the injections as soon as your doctor thinks it is appropriate.
UPRAJECT is indicated to treat :
Gastroesophageal reflux disease (GERD), an inflammation of the oesophagus (the tube connecting the throat to the stomach) accompanied by reflux of stomach acid.
Ulcers of the stomach and duodenum.
Zollinger-Ellison syndrome and other conditions that cause excessive production of gastric acid.
> DOSAGE AND METHOD OF ADMINISTRATION
Mode of administration: Intravenous
Frequency of administration: Your nurse or doctor will give you the daily dose as an injection into a vein over 2 to 15 minutes.
Dosage: The recommended dose is as follows:
Stomach ulcers, duodenal ulcers and reflux oesophagitis
One vial (40 mg pantoprazole) per day.
Long-term treatment of Zollinger-Ellison syndrome and other conditions causing excessive gastric acid production
Two vials (80 mg pantoprazole) per day.
Your doctor may need to adjust the dose later depending on how much stomach acid you produce. If your doctor prescribes more than two vials (80 mg) per day, the injections will be divided into two equal doses. Your doctor may prescribe a temporary dose of more than 4 vials (160 mg) per day. If rapid control of acid secretion is required, an initial dose of 160 mg (four vials) should provide sufficient acid reduction.
Patients with liver problems
In case of severe liver problems, the daily injection should be limited to 20 mg (half a vial).
Prescription medicine. Ask your doctor for advice.