> THERAPEUTIC INDICATION
Treatment of uncomplicated Plasmodium falciparum malaria including mixed form infections involving P. falciparum and the treatment of infections resistant to most other antimalarial drugs in adults, children and infants over 5 kg.
Consideration should be given to current recommendations for the appropriate use of antimalarial treatments.

> DOSAGE AND ADMINISTRATION
Dosage
Adults and children 12 years of age or older and weighing 35 kg or more:
The total dose should be given in 6 doses of 4 tablets (i.e. 24 tablets) spread over a total of 60 hours according to the following schedule:
First dose at the time of diagnosis: 4 tablets.
Then 5 doses of 4 tablets 8, 24, 36, 48 and 60 hours after the first dose.

Body weight from 25 kg to less than 35 kg:
First dose at diagnosis: 3 tablets
Then 5 doses of 3 tablets 8, 24, 36, 48 and 60 hours after the first dose.

Body weight 15 kg to less than 25 kg:
First dose at diagnosis: 2 tablets
Then 5 doses of 2 tablets 8, 24, 36, 48 and 60 hours after the first dose.

Body weight 5 kg to less than 15 kg:
First dose at time of diagnosis: 1 tablet.
Then 5 doses of 1 tablet 8, 24, 36, 48 and 60 hours after the first dose.

Method of administration
Tablets for oral administration.
Dissolve the tablet in a milk drink or water, shake the contents and drink.
In order to improve the absorption of the active ingredients, Cofantrine should be taken with a meal or with a milk drink. In case of vomiting within one hour of taking, a full dose should be re-administered.

This medicine is subject to medical prescription, ask your doctor or pharmacist for advice.