> THERAPEUTIC INDICATION
Treatment of uncomplicated Plasmodium falciparum malaria, including mixed form infections involving P. falciparum and treatment of infections resistant to most other antimalarial drugs in adults.
Consideration should be given to current recommendations for the appropriate use of antimalarial treatments.

> DOSAGE AND ADMINISTRATION
Dosage
The total dose should be given in 6 doses of 1 tablet, spread over a total of 60 hours, according to the following schedule
First dose at the time of diagnosis: 1 tablet.
Then 5 doses of 1 tablet at 8, 24, 36, 48 and 60 hours after the first dose.

Method of administration
Tablets for oral administration.
In order to improve the absorption of the active ingredients, Cofantrine should be taken with a meal or with a milk drink. Cofantrine may be used with water in case of food intolerance, but systemic exposure may be reduced. If vomiting occurs within one hour, a full dose should be re-administered.

This medicine is subject to medical prescription, ask your doctor or pharmacist for advice.